Human Ribonucleoside-diphosphate Reductase Large Subunit, RRM1 ELISA Kit, 96T Serum PubMed: 15194700

PubMed: 15194700

Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins

Mutations in this gene have been associated with congenital myasthenic syndrome

belongs to the BAGE family

endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane

Human Ribonucleoside-diphosphate Reductase Large Subunit, RRM1 ELISA Kit, 96T Serum PubMed: 15194700