AF1L2 Polyclonal Antibody, 50ul Cryogenic Vials The gene is located within

The gene is located within the Smith-Magenis syndrome region on chromosome 17

MIM 606083)

These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity

This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues

The encoded protein may play roles in blood vessel maturation and hematopoeisis

AF1L2 Polyclonal Antibody, 50ul Cryogenic Vials The gene is located withinMay play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC regulated transcription activation. PTM: Tyrosine phosphorylated (by SRC). Contains 2 PH domains. subunit: Interacts with SRC. Interacts with LCK when tyrosine phosphorylated. tissue specificity: Detected in spleen and thyroid and at lower levels in kidney brain lung and pancreas.