TPD53 Polyclonal Antibody, 100ul Centrifuges but not in normal immortal

but not in normal immortal melanocytes

Alternatively spliced transcript variants have been reported for this gene

Plays a role in the invasiveness of cancer cells

This gene lies within the major histocompatibility complex on chromosome 6

This gene has a pseudogene on chromosome 7

TPD53 Polyclonal Antibody, 100ul Centrifuges but not in normal immortalThis gene encodes a member of a family of proteins that contain coiled coil domains and may form hetero or homomers. The encoded protein is involved in cell proliferation and calcium signaling. It also interacts with the mitogen activated protein kinase kinase kinase 5 (MAP3K5 ASK1) and positively regulates MAP3K5 induced apoptosis. Multiple alternatively spliced transcript variants have been observed.