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HLA-DO Alpha Polyclonal Antibody, 100ul Biomatrix Recognizes the substrate consensus sequence

SKU: 91073008403

4.6
USD123.75 USD161.75

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HLA-DO Alpha Polyclonal Antibody, 100ul Biomatrix Recognizes the substrate consensus sequenceHLA DOA belongs to the HLA class II alpha chain paralogues. HLA DOA forms a heterodimer with HLA DOB. The heterodimer, HLA DO, is found in lysosomes in B cells and regulates HLA DM mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

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Description

Recognizes the substrate consensus sequence

The protein encoded by NOP56 is similar in sequence to Nop56p and is also found in the nucleolus

DLG-like (see DLG1

There are six pseudogenes of this gene found on chromosomes 2

which shift from the inactive to the active state through the action of RALGDS (MIM 601619)

HLA-DO Alpha Polyclonal Antibody, 100ul Biomatrix Recognizes the substrate consensus sequenceHLA DOA belongs to the HLA class II alpha chain paralogues. HLA DOA forms a heterodimer with HLA DOB. The heterodimer, HLA DO, is found in lysosomes in B cells and regulates HLA DM mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

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