STX6 Polyclonal Antibody, 50ul Liquid Handling SHC1 (SHC adaptor protein 1)

SHC1 (SHC adaptor protein 1) encodes three main isoforms that differ in activities and subcellular location

The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage

With a working volume of 300-400 mL and TC-Treated surface

A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases

Mutations in this gene may cause transient infantile liver failure

STX6 Polyclonal Antibody, 50ul Liquid Handling SHC1 (SHC adaptor protein 1)