Cadherin-8 Polyclonal Antibody, 50ul Multiplex Immunoassays Reduced expression of this gene

Reduced expression of this gene results in an increase in GLUT4 levels at the plasma membrane| suggesting that this protein is important in intracellular retention of GLUT4 under basal conditions

CNNM2 encodes a member of the ancient conserved domain containing protein family

the protein may act to transmit signals in natural killer cells and platelets

such as controlling the regulation of the cell cycle at the G1 to S phase transition

including the BRCA1-A complex and the BRISC complex

Cadherin-8 Polyclonal Antibody, 50ul Multiplex Immunoassays Reduced expression of this geneCDH8 encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium dependent cell cell adhesion. Mature cadherin proteins are composed of a large N terminal extracellular domain, a single membrane spanning domain, and a small, highly conserved C terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity