Oct-3/4 Monoclonal Antibody, 50ul[BT-MCA0953] Hybridoma Antibody Sequencing A missense mutation in RBSN

A missense mutation in RBSN is associated with a defect in the early endocytic pathway

Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors

elongins B and C

and contains one protein kinase domain

and thus acts as a regulator of angiogenesis

Oct-3/4 Monoclonal Antibody, 50ul[BT-MCA0953] Hybridoma Antibody Sequencing A missense mutation in RBSNThis gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG translation initiation