APC5 Polyclonal Antibody, 100ul Cell Dissociation Pharmacodynamics

Pharmacodynamics

Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis

High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus

and its SH2 domain binds tyrosine phosphorylated sequences

These proteins share considerable sequence similarity over the N-terminal portion of the molecule

APC5 Polyclonal Antibody, 100ul Cell Dissociation PharmacodynamicsANAPC5 encodes a tetratricopeptide repeat containing component of the anaphase promoting complex cyclosome (APC C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B type cyclins for 26S proteasome mediated degradation through ubiquitination. The encoded protein (anaphase promoting complex subunit 5) is required for the proper ubiquitination function of APC C and for the