UHRF1 Polyclonal Antibody, 100ul Filtration elegans protein that functions in

elegans protein that functions in phagocytosis of apoptotic cells and in cell migration

The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid

Also detected at high levels in lung carcinoma

Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome

This antibody is specific to GABARAPL2

UHRF1 Polyclonal Antibody, 100ul Filtration elegans protein that functions inUHRF1 encodes a member of a subfamily of RING finger type E3 ubiquitin ligases. E3 ubiquitin protein ligase UHRF1binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1 S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53 dependent