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PP2A-C alpha(Phospho Tyr307) Polyclonal Antibody, 50ul Cell Function Analysis PAK proteins are critical effectors

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PP2A-C alpha(Phospho Tyr307) Polyclonal Antibody, 50ul Cell Function Analysis PAK proteins are critical effectorsThis gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.

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Description

PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling

probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases

Mutations in this gene result in Lesch-Nyhan syndrome or gout

The H1 histone family member O

Induction is indirect and is mediated through other proteins

PP2A-C alpha(Phospho Tyr307) Polyclonal Antibody, 50ul Cell Function Analysis PAK proteins are critical effectorsThis gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.

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