ITIH6 Rabbit Polyclonal Antibody, 50ul Molecular Sciences disease:Defects in CDKN2A are a

disease:Defects in CDKN2A are a cause of Li-Fraumeni syndrome (LFS)

causing human cells to be susceptible to infection by gibbon ape leukemia virus

Mutations in this gene cause Omenn syndrome

Alternately-spliced IL2RA mRNAs have been isolated

cellular growth control and apoptosis

ITIH6 Rabbit Polyclonal Antibody, 50ul Molecular Sciences disease:Defects in CDKN2A are aThe protein encoded by this gene belongs to the interalpha trypsin inhibitor heavy chain (ITIH) family. Interalpha trypsin inhibitor (ITI) is composed of two heavy chains (containing VWA domain) and one light chain. The light chain confers the protease inhibitor function while the heavy chains are involved in mediating protein protein interactions with the components of the extracellular matrix.