IGF-IR Polyclonal Antibody, 100ul[BT-AP04396] Cellular Function Assays Polymorphisms in PGC are associated

Polymorphisms in PGC are associated with susceptibility to gastric cancers

The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest| and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells

The alpha and alpha' chains contain the catalytic site

that supplies calcium to cardiac muscle

which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs

IGF-IR Polyclonal Antibody, 100ul[BT-AP04396] Cellular Function Assays Polymorphisms in PGC are associatedInsulin like growth factor 1 receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding