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Tie-2 Polyclonal Antibody, 50ul[BT-AP09018] Aspirating Pipets The protein functions by blocking

SKU: 88245678392

4.1
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Tie-2 Polyclonal Antibody, 50ul[BT-AP09018] Aspirating Pipets The protein functions by blockingTEK (TEK receptor tyrosine kinase) encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin like domains, three epidermal growth factor (EGF) like domains and three fibronectin type III repeats. The ligand angiopoietin 1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in TEK

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Description

The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt

Defects in this gene are also one of the causes of congenital stationary night blindness

The encoded protein is a serum protein that is selectively secreted by cytotoxic lymphocytes and may be involved in cytotoxic lymphocyte-mediated immunity

Multiple family members are located on the X chromosome

and it may contribute to the antiviral activity of CD8 (+) T-cells

Tie-2 Polyclonal Antibody, 50ul[BT-AP09018] Aspirating Pipets The protein functions by blockingTEK (TEK receptor tyrosine kinase) encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin like domains, three epidermal growth factor (EGF) like domains and three fibronectin type III repeats. The ligand angiopoietin 1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in TEK

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