Human Tek Tyrosine Kinase, Endothelial, TIE2 ELISA Kit, 96T Contamination Detection & Removal Mutations in the human MCOLN1

Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al

tumor growth

Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules

cytokine secretion and the inflammatory response (By similarity)

The protein encoded by this gene binds to the beta-amyloid precursor protein

Human Tek Tyrosine Kinase, Endothelial, TIE2 ELISA Kit, 96T Contamination Detection & Removal Mutations in the human MCOLN1Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF) induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. [Isoform eNOS13C]: Lacks eNOS activity, dominant negative form that may down regulate eNOS activity by forming heterodimers with isoform 1.