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LAT Polyclonal Antibody, 20ul[BT-AP04958] Lentiviral Packaging AIRE encodes a transcriptional regulator

SKU: 87995777840

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LAT Polyclonal Antibody, 20ul[BT-AP04958] Lentiviral Packaging AIRE encodes a transcriptional regulatorThe protein encoded by LAT (linker for activation of T cells) is phosphorylated by ZAP 70 Syk protein tyrosine kinases following activation of the T cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling

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Description

AIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein

KCNJ16 may be involved in the regulation of fluid and pH balance

The product of CLCN7 belongs to the CLC chloride channel family of proteins

which participate in the beta-oxidation of fatty acids in mitochondria

Increased expression of CCDC88A and phosphorylation of the encoded protein may play a role in cancer metastasis

LAT Polyclonal Antibody, 20ul[BT-AP04958] Lentiviral Packaging AIRE encodes a transcriptional regulatorThe protein encoded by LAT (linker for activation of T cells) is phosphorylated by ZAP 70 Syk protein tyrosine kinases following activation of the T cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling

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