Histone H4 (Acetyl Lys91) Polyclonal Antibody, 50ul Filtration and their phosphorylation is essential

and their phosphorylation is essential for the Catalytic activity of the N-terminal kinase domain

Defects in this gene cause complement factor I deficiency

Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lact

This protein may also affect cytoskeletal-membrane organization

The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain domain

Histone H4 (Acetyl Lys91) Polyclonal Antibody, 50ul Filtration and their phosphorylation is essentialHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.