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Ret Polyclonal Antibody, 100ul[BT-AP07761] Enzyme Activity Assays Studies of the orthologous gene

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Ret Polyclonal Antibody, 100ul[BT-AP07761] Enzyme Activity Assays Studies of the orthologous geneRET (ret proto oncogene), a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell surface molecules that transduce signals for cell growth and differentiation. RET plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in RET are associated with the disorders multiple endocrine neoplasia, type IIA, multiple

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Description

Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells

ensuring accurate results and optimal performance

Mutations in this gene are associated with spondylometaphyseal dysplasia with cone-rod dystrophy

This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol| a precursor of phosphatidylinositol| and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1|4|5-trisphosphate and diacylglycerol

a disease associated with an heterogeneous group of cerebellar disorders

Ret Polyclonal Antibody, 100ul[BT-AP07761] Enzyme Activity Assays Studies of the orthologous geneRET (ret proto oncogene), a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell surface molecules that transduce signals for cell growth and differentiation. RET plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in RET are associated with the disorders multiple endocrine neoplasia, type IIA, multiple

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