c-Abl(Phospho-Tyr412) Rabbit Polyclonal Antibody, 100ul Protein Analysis |PTM:The two subunits are derived

|PTM:The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8

bundling and anchoring microtubules to the centrosomes

Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2

such as ARSK

Mutations in PNPT1 have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70

c-Abl(Phospho-Tyr412) Rabbit Polyclonal Antibody, 100ul Protein Analysis |PTM:The two subunits are derivedThis gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress. The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation suggesting a