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Kininogen 1 Rabbit Polyclonal Antibody, 100ul Lentiviral Packaging The encoded protein is involved

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Kininogen 1 Rabbit Polyclonal Antibody, 100ul Lentiviral Packaging The encoded protein is involvedThis gene uses alternative splicing to generate two different proteins high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is

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Description

The encoded protein is involved in several cellular processes| including autophagic vesicle formation| mitochondrial quality control after oxidative damage| negative regulation of the innate antiviral immune response| lymphocyte development and proliferation| MHC II antigen presentation| adipocyte differentiation| and apoptosis

The product of CRK has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways

are a family of type 1 transmembrane proteins each having a unique expression pattern

Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination

Reduced expression of GDF9 may be associated with polycystic ovary syndrome and mutations in this gene may be more common in mothers of dizygotic twins

Kininogen 1 Rabbit Polyclonal Antibody, 100ul Lentiviral Packaging The encoded protein is involvedThis gene uses alternative splicing to generate two different proteins high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is

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