AFG3L2 Polyclonal Antibody, 20ul Sample Library Tubes CDK11A (cyclin dependent kinase 11A)

CDK11A (cyclin dependent kinase 11A) encodes a member of the serine/threonine protein kinase family

Mutations in this gene are associated with platelet-type bleeding disorders| which are characterized by a failure of platelet aggregation| including Glanzmann thrombasthenia

The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF)

effectively minimizing sample loss

however| the expression pattern suggests a role in lipid homeostasis in cells of the immune system

AFG3L2 Polyclonal Antibody, 20ul Sample Library Tubes CDK11A (cyclin dependent kinase 11A)This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.