Smad2 Polyclonal Antibody, 100ul[BT-AP08381] Adenovirus Packaging This gene is a member

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain

Multiple transcript variants for this gene exist

Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies

radiation hybrid mapping localized it to 9p13-p12

Also functions as a receptor for various alkaloids and psychoactive substances

Smad2 Polyclonal Antibody, 100ul[BT-AP08381] Adenovirus Packaging This gene is a memberMothers against decapentaplegic homolog 2 encoded by SMAD2 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF) beta, and thus regulates multiple cellular