STK36 Polyclonal Antibody, 100ul Cell Labeling & Imaging Protein inhibitor of activated STAT

Protein inhibitor of activated STAT 1 plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways

and expressed in testis and in a significant fraction of tumors of various histological types

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The encoded protein catalyzes the 2-thiolation of uridine on the wobble positions of tRNA(Lys)| tRNA(Glu)| and tRNA(Gln)| resulting in the formation of 5-taurinomethyl-2-thiouridine moieties

Alternatively spliced transcript variants encoding multiple isoforms have been observed for TCF3

STK36 Polyclonal Antibody, 100ul Cell Labeling & Imaging Protein inhibitor of activated STATSTK36 encodes a member of the serine threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia.