TXLNA Polyclonal Antibody, 20ul Gene Editing Beta subunit gene mutations lead

Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II)

Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome

The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription

The membrane-associated protein encoded by ABCB10 is a member of the superfamily of ATP-binding cassette (ABC) transporters

Overexpression of PDK2 may play a role in both cancer and diabetes

TXLNA Polyclonal Antibody, 20ul Gene Editing Beta subunit gene mutations leadWas originally (PubMed: 8327514) thought to be a high molecular weight interleukin (IL 14 or IL14).,May be involved in intracellular vesicle traffic and potentially in calcium dependent exocytosis in neuroendocrine cells.,Belongs to the taxilin family.,subunit: Binds to the C terminal coiled coil region of syntaxin family members STX1A, STX3A and STX4A, but not when these proteins are complexed with SNAP25, VAMP2 or STXBP1, suggesting that it