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P-Selectin Polyclonal Antibody, 100ul Buffers & Solutions Alternatively spliced transcript variants have

SKU: 85262340647

4.3
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P-Selectin Polyclonal Antibody, 100ul Buffers & Solutions Alternatively spliced transcript variants haveSELP encodes a 140 kDa protein that is stored in the alpha granules of platelets and Weibel Palade bodies of endothelial cells. P selectin redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils

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Description

Alternatively spliced transcript variants have been found for

implying different ligand specificity

The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules

Leukotrienes are important mediators of a number of inflammatory and allergic conditions

This protein (apoptotic peptidase activating factor 1) contains several copies of the WD-40 domain

P-Selectin Polyclonal Antibody, 100ul Buffers & Solutions Alternatively spliced transcript variants haveSELP encodes a 140 kDa protein that is stored in the alpha granules of platelets and Weibel Palade bodies of endothelial cells. P selectin redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils

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