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BID Polyclonal Antibody, 50ul[BT-AP00897] Apoptosis & Autophagy Mutations in this gene have

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BID Polyclonal Antibody, 50ul[BT-AP00897] Apoptosis & Autophagy Mutations in this gene haveBID encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. BH3 interacting domain death agonist is a member of the BCL 2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase 8 (CASP8); CASP8 cleaves BH3 interacting domain death agonist, and the COOH terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript

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Description

Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus

Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling

The encoded protein contains an N-terminal actin-binding domain

and angiogenesis

It activates transcription by binding to the E box (5'-CANNTG-3')

BID Polyclonal Antibody, 50ul[BT-AP00897] Apoptosis & Autophagy Mutations in this gene haveBID encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. BH3 interacting domain death agonist is a member of the BCL 2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase 8 (CASP8); CASP8 cleaves BH3 interacting domain death agonist, and the COOH terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript

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