TRAF7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos The consequence of CD5 binding

The consequence of CD5 binding to its cognate receptor is still in question and likely plays a role in thymic selection

A mutations in this gene is associated with autosomal dominant macrothrombocytopenia

It encodes a protein (Jun proto-oncogene

NEGR1 is a Protein Coding gene

Cleft palate with ankyloglossia

TRAF7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos The consequence of CD5 bindingTumor necrosis factor (TNF; see MIM 191160) receptor associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N terminal cysteine histidine rich region containing zinc RING and or zinc finger motifs; a coiled coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self association and receptor binding.