PBIP1 Rabbit Polyclonal Antibody, 50ul Shaker&Mixing Involved in signal transduction through

Involved in signal transduction through the Wnt pathway

In addition to possessing several cell adhesion molecule-like domains

DNA-binding domain

The encoded protein also promotes transcription at the c-fos gene

Among its related pathways are Metabolism and Sphingolipid signaling pathway

PBIP1 Rabbit Polyclonal Antibody, 50ul Shaker&Mixing Involved in signal transduction throughThe protein encoded by this gene interacts with the PBX1 homeodomain protein inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein which is primarily cytosolic but can shuttle to the nucleus also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer brain tumors and lung cancer. Several transcript variants encoding different isoforms have been found for