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Patched Polyclonal Antibody, 50ul DNA Oligo Synthesis Its depletion enhances the cytotoxic

SKU: 84116283615

4.1
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Patched Polyclonal Antibody, 50ul DNA Oligo Synthesis Its depletion enhances the cytotoxicPTCH1 (patched 1) encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of PTCH1 have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas,

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Description

Its depletion enhances the cytotoxic action of the chemotherapeutic drugs

Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities

and promotes cell proliferation

The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway

16 epidermal growth factor (EGF)-like

Patched Polyclonal Antibody, 50ul DNA Oligo Synthesis Its depletion enhances the cytotoxicPTCH1 (patched 1) encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of PTCH1 have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas,

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