Human G-protein Coupled Receptor 55, GPR55 ELISA Kit, 96T Liquid Storage Consumables Upon ligand binding it associates

Upon ligand binding it associates with mitochondria antiviral signaling protein (MAVS/IPS1) which activates the IKK-related kinases: TBK1 and IKBKE which phosphorylate interferon regulatory factors: IRF3 and IRF7 which in turn activate transcription of antiviral immunological genes

PubMed: 28302677)

with the release of carbon dioxide and GDP

It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2

A cytochrome P450 monooxygenase that catalyzes the conversion of C19 androgens

Human G-protein Coupled Receptor 55, GPR55 ELISA Kit, 96T Liquid Storage Consumables Upon ligand binding it associatesMay be involved in hyperalgesia associated with inflammatory and neuropathic pain (By similarity). Receptor for L alpha lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. Putative cannabinoid receptor. May play a role in bone physiology by regulating osteoclast number and function.