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Ku-70 Polyclonal Antibody, 100ul[BT-AP04897] Protein Post-translational Modification This gene encodes a protein

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Ku-70 Polyclonal Antibody, 100ul[BT-AP04897] Protein Post-translational Modification This gene encodes a proteinThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0

SMC3 and either SMC1B or the protein encoded by this gene

The encoded protein appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance

the major source of B cell precursors

The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade

Ku-70 Polyclonal Antibody, 100ul[BT-AP04897] Protein Post-translational Modification This gene encodes a proteinThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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