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p53 Monoclonal Antibody(6C4), 100ul Immunology The protein forms a complex

SKU: 82998366826

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p53 Monoclonal Antibody(6C4), 100ul Immunology The protein forms a complexThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

The protein forms a complex with the RAD50 homolog

and various head and neck cancers

Rho-associated kinase (Rho-kinase)

May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development

Probably inactive as a glycosidase

p53 Monoclonal Antibody(6C4), 100ul Immunology The protein forms a complexThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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