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IL-15 Polyclonal Antibody, 20ul Reservoirs The promoter polymorphism of IL12B

SKU: 82707248156

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IL-15 Polyclonal Antibody, 20ul Reservoirs The promoter polymorphism of IL12BThe protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine

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Description

The promoter polymorphism of IL12B has been reported to be associated with the severity of atopic and non-atopic asthma in children

It is a secreted protein and exists in either a single chain form or a clipped

This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M

Mutations associated with this gene cause autosomal recessive spastic paraplegia 13

Associates with the 9-1-1 complex

IL-15 Polyclonal Antibody, 20ul Reservoirs The promoter polymorphism of IL12BThe protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine

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