Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 20ul Buffers & Solutions Mutations in ELOVL5 have been

Mutations in ELOVL5 have been associated with spinocerebellar ataxia-38 (SCA38)

Activating transcription factor 2 may also be involved in cell's DNA damage response independent of its role in transcriptional regulation

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This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M

and being expressed in vascular endothelium cells and binding to L-selectin

Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 20ul Buffers & Solutions Mutations in ELOVL5 have beenSignal transducer and activator of transcription that mediates signaling by type I IFNs (IFN alpha and IFN beta). Following type I IFN binding to cell surface receptors Jak kinases (TYK2 and JAK1) are activated leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize associate with ISGF3G IRF 9 to form a complex termed ISGF3 transcription factor that enters the nucleus. ISGF3 binds to the IFN stimulated response