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p53 Polyclonal Antibody, 20ul[BT-AP06819] Transporters Alternatively spliced transcript variants have

SKU: 82197695989

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p53 Polyclonal Antibody, 20ul[BT-AP06819] Transporters Alternatively spliced transcript variants haveTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Alternatively spliced transcript variants have been described for LAIR2

suggesting that they are derived from recent gene duplication events

Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of CRHR1

YOD1 deubiquitinase by YOD1 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain

is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis

p53 Polyclonal Antibody, 20ul[BT-AP06819] Transporters Alternatively spliced transcript variants haveTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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