ELL Polyclonal Antibody, 20ul Cell Senescence The encoded protein (ALMS1

The encoded protein (ALMS1

This protein is not restricted to leukemic cells

The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling

and remains highly transparency)

as a sensor for oxidative stress

ELL Polyclonal Antibody, 20ul Cell Senescence The encoded protein (ALMS1ELL is an elongation factor that inrecase the catalytic rate of RNA polymerase II transcription via suppressing transient pausing by the polymerase at multiple sites along the DNA. Also it's the second elongation factor to be involved in oncogenesis which is a transcription factor regulated by the product of the von Hippel Lindau tumor suppressor. There are two transcirpts variants in mRNA level, one is 4. 4 kb transcript and the other is 2. 8 kb