MDM2 Polyclonal Antibody, 100ul[BT-AP05300] Multiplex Immunoassays tissue specificity:Highly expressed in placental

tissue specificity:Highly expressed in placental JEG-3 cells and very low levels of expression in non-steroidogenic cells

The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities

this protein fragment has frequently been used to confer specific DNA binding in experiments examining transcriptional activation functions of heterologous proteins

Data suggest that the similar protein in mouse plays an important role in trabeculation of the embryonic heart

also known as F-actin bundling domain

MDM2 Polyclonal Antibody, 100ul[BT-AP05300] Multiplex Immunoassays tissue specificity:Highly expressed in placentalMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript