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PTP22 Polyclonal Antibody, 100ul Enzymes & Activity Assays 17-alpha-hydroxylase/17

SKU: 81191744384

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PTP22 Polyclonal Antibody, 100ul Enzymes & Activity Assays 17-alpha-hydroxylase/17PTPN22 encodes of member of the non receptor class 4 subfamily of the protein tyrosine phosphatase family. The protein tyrosine phosphatase, non receptor type 22 is a lymphoid specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1

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Description

17-alpha-hydroxylase/17

1| where most DUF1220 domains are located| have been implicated in a number of developmental and neurogenetic diseases such as microcephaly| macrocephaly| autism| schizophrenia| mental retardation| congenital heart disease| neuroblastoma| and congenital kidney and urinary tract anomalies

Members of this protein family form part of the cytomatrix at the active zone (CAZ) complex and function as regulators of neurotransmitter release

Participates in Wnt signaling

CCL4 attracts a variety of immune cells to sites of microbial infection as well as to other pathologic inflammation such as allergic asthma and ischemic myocardium

PTP22 Polyclonal Antibody, 100ul Enzymes & Activity Assays 17-alpha-hydroxylase/17PTPN22 encodes of member of the non receptor class 4 subfamily of the protein tyrosine phosphatase family. The protein tyrosine phosphatase, non receptor type 22 is a lymphoid specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1

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