DSE Rabbit Polyclonal Antibody, 100ul Centrifuges Adaptins are important components of

Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes

Alternative splicing of this gene generates 2 transcript variants| but the full length nature of one of the variants has not been defined

This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins

Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease

down-regulated by phorbol 12-myristate 13-acetate

DSE Rabbit Polyclonal Antibody, 100ul Centrifuges Adaptins are important components ofThe protein encoded by this gene is a tumor rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D glucuronic acid to L iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA A24 restricted and tumor specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural