NFκB-p100(Phospho Ser872) Polyclonal Antibody, 100ul Immune Cell Analysis The encoded protein requires synaptonemal

The encoded protein requires synaptonemal complex protein 3

it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly

A translocation involving the MLL gene and SEPT5 has also been reported in patients with acute myeloid leukemia

Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6

Additional splice variants have also been reported

NFκB-p100(Phospho Ser872) Polyclonal Antibody, 100ul Immune Cell Analysis The encoded protein requires synaptonemalThis gene encodes a subunit of the transcription factor complex nuclear factor kappa B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full length protein is co translationally processed into a p52 active