SIX3 Polyclonal Antibody, 50ul Purification Birt-Hogg-Dube syndrome and Canavan disease

Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17

The tyrosine kinase non receptor 2 may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway

Seems to have a role in retrograde membrane traffic at the level of the Golgi complex

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Inhibits CREB activity by phosphorylating and repressing TORCs

SIX3 Polyclonal Antibody, 50ul Purification Birt-Hogg-Dube syndrome and Canavan diseaseThis gene encodes a member of the sine oculis homeobox transcription factor family. The encoded protein plays a role in eye development. Mutations in this gene have been associated with holoprosencephaly type 2.