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PACS1 Polyclonal Antibody, 50ul In vitro Assessment centronuclear

SKU: 79925645803

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DKK162.00 DKK184.00

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PACS1 Polyclonal Antibody, 50ul In vitro Assessment centronuclearThis gene encodes a protein with a putative role in the localization of trans Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV 1 Nef mediated downregulation of cell surface MHC I molecules to the TGN, thereby

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Description

centronuclear

The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C

Activates the JUN N-terminal pathway

hypophosphorylated form of the protein binds transcription factor E2F1

Additional transcript variants have been described

PACS1 Polyclonal Antibody, 50ul In vitro Assessment centronuclearThis gene encodes a protein with a putative role in the localization of trans Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV 1 Nef mediated downregulation of cell surface MHC I molecules to the TGN, thereby

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