TLR13 Polyclonal Antibody, 50ul RNA Synthesis MOB kinase activator 3C encoded

MOB kinase activator 3C encoded by MOB3C is similar to the yeast Mob1 protein

and a short carboxy-terminal cytoplasmic tail

Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity

Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene

Several transcript variants encoding many different isoforms have been found for EDA

TLR13 Polyclonal Antibody, 50ul RNA Synthesis MOB kinase activator 3C encodedThe TLRs form a family of ligand binding proteins that engage a variety of microbial products, that on binding, activate signaling cascades leading to the synthesis of proinflammatory molecules. TLR13 is found in mouse and participates in the innate immune response to microbial agents. It acts via MYD88 and TRAF6, leading to NF kappa B activation, cytokine secretion and the inflammatory response.