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HXD9 Polyclonal Antibody, 50ul Live Cell Imaging misfolded proteins are retrotranslocated to

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HXD9 Polyclonal Antibody, 50ul Live Cell Imaging misfolded proteins are retrotranslocated toThis gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31 2q37 chromosome regions.

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Description

misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD)

This gene encodes the alpha chain of type XXI collagen| a member of the FACIT (fibril-associated collagens with interrupted helices) collagen family

Low expression of this gene may be related to higher survival rates in breast cancer patients

This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain

The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature

HXD9 Polyclonal Antibody, 50ul Live Cell Imaging misfolded proteins are retrotranslocated toThis gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31 2q37 chromosome regions.

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