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MALD2 Polyclonal Antibody, 100ul sgRNA Library Construction The encoded protein has sequence

SKU: 79123031639

4.1
SEK123.75 SEK167.75

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MALD2 Polyclonal Antibody, 100ul sgRNA Library Construction The encoded protein has sequenceThe protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene.

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Description

The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains

strong ectopic expression has been detected in ovarian adenocarcinoma

FAS and FADD

This protein| along with TAB1 and MAP3K7| also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK)| which may regulate the development and function of osteoclasts

This is one of two genes encoding the galactoside 2-L-fucosyltransferase enzyme

MALD2 Polyclonal Antibody, 100ul sgRNA Library Construction The encoded protein has sequenceThe protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene.

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