Rb Polyclonal Antibody, 50ul[BT-AP07692] Cell Senescence and peripheral blood

and peripheral blood

It plays an important role in neuronal development and function

and axial skeleton

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG)

and being expressed in vascular endothelium cells and binding to L-selectin

Rb Polyclonal Antibody, 50ul[BT-AP07692] Cell Senescence and peripheral bloodThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.