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NFκB-p65(Phospho Thr505) Polyclonal Antibody, 20ul 3D Culture Mutations in PSAP have been

SKU: 78549749922

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NFκB-p65(Phospho Thr505) Polyclonal Antibody, 20ul 3D Culture Mutations in PSAP have beenNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene, RELA. Four

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Description

Mutations in PSAP have been associated with Gaucher disease and metachromatic leukodystrophy

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and transformation

a zinc finger domain

Multiple transcript variants encoding different isoforms have been found for NFYC

NFκB-p65(Phospho Thr505) Polyclonal Antibody, 20ul 3D Culture Mutations in PSAP have beenNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene, RELA. Four

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