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AChRBeta1 Polyclonal Antibody, 50ul Pathway and Network Analysis This gene is biallelically expressed

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AChRBeta1 Polyclonal Antibody, 50ul Pathway and Network Analysis This gene is biallelically expressedThe muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. CHRNB encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion conducting channel across the plasma membrane. Mutations in this gene are associated with slow channel congenital myasthenic syndrome.

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Description

This gene is biallelically expressed in the brain| however| only the paternal allele is expressed in the testis (PMID:18055845)

The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein

which is produced by the pancreatic acinar cells

2-methylacetoacetic acid

Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis

AChRBeta1 Polyclonal Antibody, 50ul Pathway and Network Analysis This gene is biallelically expressedThe muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. CHRNB encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion conducting channel across the plasma membrane. Mutations in this gene are associated with slow channel congenital myasthenic syndrome.

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