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TGF beta RIII(Phospho Thr842) Polyclonal Antibody, 50ul Thermo Mix is located in the mitochondria

SKU: 77837946294

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TGF beta RIII(Phospho Thr842) Polyclonal Antibody, 50ul Thermo Mix is located in the mitochondriaThis locus encodes the transforming growth factor (TGF) beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co receptor with other TGF beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been

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Description

is located in the mitochondria and expressed in extra-hepatic tissues

The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells

a protein involved in the initiation of DNA replication

This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family| whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains

Gene Ontology (GO) annotations related to this gene include L-serine transmembrane transporter activity

TGF beta RIII(Phospho Thr842) Polyclonal Antibody, 50ul Thermo Mix is located in the mitochondriaThis locus encodes the transforming growth factor (TGF) beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co receptor with other TGF beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been

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