Nibrin Polyclonal Antibody, 20ul[BT-AP06022] Centrifugal Filter but their full-length natures have

but their full-length natures have not been determined

This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes

as well as in the regulation of water excretion and cardiovascular functions

Multiple alternatively spliced variants

CHRNA1 encodes an alpha subunit that plays a role in acetlycholine binding/channel gating

Nibrin Polyclonal Antibody, 20ul[BT-AP06022] Centrifugal Filter but their full-length natures haveMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.