PIASy Polyclonal Antibody, 50ul Culture Tubes The encoded protein is a

The encoded protein is a member of a family of closely related cyclic adenosine monophosphate-binding channel proteins

The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks

Type I interferon required for maintaining basal levels of IFN-regulated genes

Mutations of this gene are associated with progressive pseudorheumatoid dysplasia

The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins

PIASy Polyclonal Antibody, 50ul Culture Tubes The encoded protein is aThe protein inhibitor of activated Stat (PIAS) proteins, which include PIAS1, PIAS3, PIASx, and PIASy, were originally characterized based on their interaction with the Stat family of transcription factors. PIAS1, PIAS3, and PIASx interact with and repress Stat1, Stat3, and Stat4, respectively. Deletion of PIAS1 leads to inhibition of interferon inducible genes and increased protection against infection. The PIAS family contains a conserved RING